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Image Search Results
Journal: Oncotarget
Article Title: Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy
doi: 10.18632/oncotarget.24327
Figure Lengend Snippet: Colon 26 ( A ) and SCCVII ( B ) tumor cells were inoculated into BALB/c and C3H mice, and treatments were started on day 0 and day 7, respectively. Control reagents (PBS or rat IgG), resiquimod (RQ), anti-PD-L1 mAb (PD-L1) and both (RQ+PD) were injected i.p. twice a week until day 17. The arrows indicate the time of treatment. Tumor volume was measured every day. The values are the mean ± SEM from three independent experiments with each group of five mice. * Statistically different ( p < 0.05). The four smaller panels on the left show the individual growth curves. The final tumor volumes on day 19 are shown in the right panels. Digital photo images of resected Colon 26 tumor masses on day 19 are shown in the lower panel of A.
Article Snippet: Female 6–7-week-old
Techniques: Injection